Infekcinės ligos ISSN 1822-8771 | eISSN 2783-6665

Egzistuoja milijonai grybelių rūšių, tačiau tik keletas šimtų, priklausančių mieliagrybių, pelėsinių, dermatofitų ar dimorfinių grybelių rūšims, žmogui gali sukelti ligą. Pačios grėsmingiausios žmonių sveikatai yra invazinės grybelinės infekcijos. Medicinos pažanga, taikomi nauji gydymo metodai, įvairios imunosupresinės būklės yra susijusios su didesne šių infekcijų rizika. Invazinės grybelinės infekcijos yra aktuali problema visame pasaulyje – jas sunku išgydyti, didėja atsparumas vaistams, o mirštamumas išlieka didelis.

The COVID-19 pandemic caused by the SARS-CoV-2 virus contributed to a global health crisis. Pregnant women are considered a vulnerable population that can develop severe SARS-CoV-2 infections due to physiological changes during pregnancy that affect a wide range of functions, causing cardiovascular instability, bleeding disorders, respiratory and immune dysfunction. These factors may adversely affect the course of COVID-19. In addition to pregnancy, a pregnant woman may have additional risk factors, including diabetes, obesity, advanced age (pregnancy >35 years), or chronic cardiovascular or respiratory disease. Early studies indicate that COVID-19 increases the risk of serious illness and death in pregnant women. In addition, COVID-19 was associated with adverse fetal outcomes as preterm birth. The mechanisms underlying the increased risk of adverse pregnancy outcomes in pregnant women with COVID-19 are not well-understood but may be related to the direct effects of SARS-CoV-2 on the placenta and the fetus, as well as the indirect effects of systemic inflammation and cytokine storm. During the pandemic, the SARS-CoV-2 delta variant in particular has been shown to be associated with severe disease. The new coronavirus variants pre-delta, as well as the omicron variant, seem to be generally associated with a milder course of disease.